Skip to main content
. 2002 Nov 1;22(21):9228–9236. doi: 10.1523/JNEUROSCI.22-21-09228.2002

Fig. 1.

Fig. 1.

Activation of microglia during light-induced retinal degeneration. A–F, Immunohistochemical analysis of normal (A–C) and light-reared (D–F) P35 rat retina using the antibodies iba1 (red in A, C,D, F) and ED1 (green in B, C,E, F). In light-degenerated retina, iba1 immunoreactivity was observed in the outer retina and double-labeled with ED1 (yellow) (F, arrowheads). G, Quantitative analysis of the ED1-positive cultured microglial cells from normal (red bar) and light-reared (green bar) P35 rat retina. Each data point represents the mean ± SEM of the values obtained from six independent experiments; *p < 0.05. H, I, Double-label immunocytochemistry of cultured microglial cells using the antibodies iba1 (red) and ED1 (green) from normal (H) and light-reared (I) P35 rat retina. GCL, Ganglion cell layer; INL, inner nuclear layer;ONL, outer nuclear layer. Scale bars, 30 μm.