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Tail immersion responses to acute thermal stimulus in wild-type (+/+) and A2A receptor knock-out (−/−) mice.a, Basal reactivity to a thermal stimulus of 55°C for wild-type (+/+) mice (n = 25) and A2Areceptor knock-out (−/−) mice (n = 20);b, basal reactivity to a thermal stimulus of 52°C for wild-type (+/+) mice (n = 55) and A2Areceptor knock-out (−/−) mice (n = 40). Error bars represent SEM. ns, Not significant.p < 0.05; significant difference between genotypes (Student's t test).
