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. 2002 Nov 1;22(21):9185–9193. doi: 10.1523/JNEUROSCI.22-21-09185.2002

Fig. 3.

Fig. 3.

Activation of D4 receptors reduced the amplitude of mIPSCs recorded from pyramidal neurons in PFC slices.A, Cumulative plots of the amplitude of mIPSCs in a PFC pyramidal neuron. Note that PD168077 (PD; 20 μm) caused a reversible leftward shift on the distribution of mIPSC amplitudes, indicative of a reduction in the sizes of mIPSCs by PD168077. B, Cumulative plots of the frequency of mIPSCs in the same cell demonstrating that the distribution of mIPSC frequency was not changed by PD168077 (20 μm). C, Representativetraces of mIPSCs recorded from the cell before (control,ctl), during bath application of PD168077, and after washout of the agonist. D, Cumulative data (means ± SEM) showing the percentage modulation of mIPSC amplitude and mIPSC frequency by PD168077 in a sample of PFC pyramidal neurons (n = 27).