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Effect of PDC and riluzole on morphine tolerance
| Group | AD50 (μg) | 95% CI (μg) |
|---|---|---|
| Saline | 4.8 | 1.3–8.2 |
| B10+SAL | 22.6 | 6.9–38.2 |
| B10+P5 | 24.4 | 3.5–45.2 |
| B10+P10 | 30.5 | 5.6–66.8 |
| B10+P20 | 68.1 | 27.7–108.5 |
| B10+R5 | 19.5 | 14.4–53.4 |
| B10+R10 | 10.5 | 4.8–25.7 |
| B10+R20 | 6.1 | 1.4–16.3 |
See the Figure 8 legend for the details for each group. Note that both B10+P20 and B10+R20 groups were significantly different from the B10+saline group based on the AD50 value and 95% CI.
