Comparison of the decreases in extrasynaptic α7 subunit mRNA levels relative to those seen for synaptic α3, β4, and α5 subunit mRNAs in CG neurons deprived of input, targets, and both synaptic partners. Data are expressed as the fold change in the absolute levels of nAChR subunit mRNA per neuron in the test condition relative to controls. For input-deprived CGs and both input- and target-deprived CGs, the sham-operated age-matched CGs are used as controls, whereas target-deprived CGs are compared with the contralateral control CG from the same embryo. The α7 mRNA data are from Figure 2, and the α3, β4, and α5 mRNA values are from Levey et al. (1995). —, Not significantly different from control values; Student'st test.