Skip to main content
. 2002 Aug 1;22(15):6331–6335. doi: 10.1523/JNEUROSCI.22-15-06331.2002

Fig. 3.

Fig. 3.

Aβ levels in Tg2576 mice treated with BAM-10 or nonspecific IgG antibody. Total Aβ is the sum of Aβ40 and Aβ42 in TBS, 2% SDS, and formic acid (FA) soluble fractions measured as described previously (Kawarabayashi et al., 2001). a, Treatment of mice with BAM-10 was not associated with a significant reduction in total Aβ or in Aβ40 or Aβ42 in any of the fractions analyzed (p values ranged from 0.2 to 0.9). Measurements represent means ± SDs. Brain Aβ levels were correlated with memory in 8.7-month-old Tg2576 mice treated with BAM-10 or nonspecific IgG antibody. b, There was a significant inverse correlation between total Aβ and probe scores in control mice treated with nonspecific IgG.c, Treatment with BAM-10 eliminated the correlation between total Aβ and probe scores.