Fig. 6.

Expression of T-type calcium channel genes in tg, lh, and stgthalamus. The three genes, Cacna1g(Cav3.1/α1G),Cacna1h (Cav3.2/α1H), andCacna1i (Cav3.3/α1I) were expressed in distinct and primarily non-overlapping patterns in coronal sections of mouse brain. Cav3.1 mRNA was detected at highest levels in neocortex and thalamus and in hippocampal dentate granule cells, with lower levels in hippocampal CA1–CA2 regions. Cav3.2 expression appeared to be restricted to hippocampal dentate gyrus and CA1–CA3 regions in the sections shown above. Cav3.3 expression was the most broadly distributed of the three T-type genes in mouse brain, with high levels of mRNA observed in nRT, habenula, hippocampal CA1 region, neocortex, and striatum. These patterns were not appreciably altered in homozygous tg,lh, or stg mutant mice.