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. 2002 Aug 1;22(15):6447–6457. doi: 10.1523/JNEUROSCI.22-15-06447.2002

Fig. 3.

Fig. 3.

Miniature endplate current traces from individual diaphragm muscle fibers of wild type (A), δS262T (B), αC418W (C), αL251T (D), and εL269F (E). The prolonged and prominent bi-exponential decay phases correlate with the open times of the mutant channels expressed in the mice (Table 1). A, Average rise, 0.42 ± 0.47 msec; τs, 1.34 msec; amplitude (Amp), 4.15 ± 1.16 nA. B, Average rise, 0.32 ± 0.09 msec; τs = 2.34 msec; Amp, 2.69 ± 0.47 nA. C, Average rise, 0.25; τ1 = 1.52, τ2 = 9.89 msec; Amp, 3.48 nA. D, Average rise, 0.18 ± 0.14 msec; τ1 = 0.72 msec, τ2 = 8.37 msec; Amp, 3.31 ± 0.65 nA. E, Average rise, 0.37 ± 0.33 msec; τ1 = 0.17 msec, τ2 = 15.87 msec; Amp, 2.58 nA. Calibration: 1 nA, 15 msec.