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Summary of neuromuscular properties in transgenic mice2-a
| Mouse line | Strength testing | MEPC duration | MEPC area | MEPC amp | Calcium overload | |||
|---|---|---|---|---|---|---|---|---|
| Rest | Exercise | AChR loss | Endplate myopathy | |||||
| Wild type | − | − | − | − | − | − | − | − |
| δS262T | + | + | − | + | − | − | − | − |
| αC418W | ++ | ++ | + | + | + | + | − | +/− |
| αL251T | ++ | ++ | − | + | ++ | +++ | − | ++ |
| ɛL269F | +++ | +++ | ++ | ++ | +++ | +++ | ++ | ++ |
Assignments of + based on rank order and magnitude change in each parameter.
