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ORX-A does not influence net whole-cell potassium currents. A, Whole-cell net K+currents isolated from area postrema neurons (with 0.1 μmTTX in aCSF) evoked by 20 mV voltage steps (5 sec) from −100 mV holding potential to +40 mV were unaffected by ORX-A exposure.B, Summary data of K+ conductances recorded before (solid) and after (open) extracellular application of ORX-A (10−8m) were not different at either the peak (squares) or the sustained currents (triangles).
