Fig. 4.
ORX-A activates nonselective cationic conductance in AP neurons. A, Top panel, Mean whole-cell currents (each trace is the mean of 5 ramps) evoked from slow depolarizing (10 mV/sec) voltage ramps before, during, and after exposure to ORX-A (10−8m).Bottom panel, Difference current obtained by subtracting the control current from the current recorded during ORX-A application. This represents the ORX-A-evoked current. B, Mean ORX-A-evoked current for responsive neurons (n = 14) and its 95% confidence interval.