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. 2002 Jul 1;22(13):5597–5605. doi: 10.1523/JNEUROSCI.22-13-05597.2002

Fig. 7.

Fig. 7.

State-dependent changes in ACh release are localized to lateral regions of the basal forebrain. ACh release is plotted as a function of the sleep/wake state for lateral and medial basal forebrain regions. There was no significant effect of arousal state on ACh release in medial basal forebrain regions. One-way ANOVA showed that ACh release in lateral sites was state-dependent (p < 0.0001). Lateral site data are based on 3530 min of dialysis, including 133 dialysis samples collected during wakefulness, 187 NREM sleep samples, and 33 REM sleep samples obtained from 31 experiments in six cats. Medial site data are based on 940 min of dialysis, including 37 dialysis samples collected during wakefulness, 53 NREM sleep samples, and four REM sleep samples obtained from seven experiments in four cats. The asteriskindicates a significant difference in ACh release between the lateral and medial basal forebrain regions.