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Effect of a neutralizing antibody against EGFR/ErbB1 on HB-EGF-stimulated incorporation of BrdU. Normoxic cultures were treated with HB-EGF or FGF-2 in the presence of anti-EGFR/ErbB1 for 24 hr and then exposed to BrdU for 4 hr, and BrdU incorporation was determined by ELISA. Data are mean ± SEM (n = 3). *p < 0.05 relative toNo antibody (ANOVA and post hoct tests).
