Table 1.

Group-I mGlu receptor antagonists fail to affect body temperature in control and MA-treated mice

Treatments	Body temperature (°C)
	60 min	180 min	300 min
Saline	37.6  ± 0.09	37.2  ± 0.15	37.2  ± 0.11
MA	39.3  ± 0.17	39.3  ± 0.18	39.2  ± 0.16
MPEP	37.5  ± 0.25	37.2  ± 0.03	37.1  ± 0.20
SIB-1893	37.4  ± 0.26	36.9  ± 0.58	37.1  ± 0.28
SIB-1757	37.4  ± 0.15	37.1  ± 0.13	37.3  ± 0.17
CPCCOEt	37.6  ± 0.21	38.1  ± 0.9	37.2  ± 0.15
MA + MPEP	39.2  ± 0.09	39.2  ± 0.13	39.4  ± 0.12
MA + SIB-1893	39.4  ± 0.10	39.6  ± 0.09	39.2  ± 0.19
MA + SIB-1757	39.5  ± 0.68	39.4  ± 0.21	39.2  ± 0.21
MA + CPCCOEt	39.3  ± 0.16	39.5  ± 0.13	39.3  ± 0.18

Body temperature was measured after three repeated injections of methamphetamine, 5 mg/kg, 2 hr apart. Effects of each compound (all at 10 mg/kg) on body temperature were measured 1 hr after each methamphetamine injection. Values are mean ± SEM of four animals for each time point.