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MHC-II immunohistochemistry with Congo red counterstaining of NCX-2216-treated transgenic mice is shown. MHC-II immunohistochemistry (black reaction product) of the frontal cortex (A) and hippocampus (C) of an APP+PS1 transgenic mouse fed the control diet from 7 to 12 months of age is shown. MHC-II immunohistochemistry of the frontal cortex (B) and hippocampus (D) of an APP+PS1 transgenic mouse fed 375 ppm NCX-2216 in diet from 7 to 12 months of age is also shown. Scale bar, 100 μm.
