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Effects of short-term NCX-2216 treatment on microglial markers in APP+PS1 mice. Animals were treated with 7.5 mg · kg−1 · d−1NCX-2216 or vehicle for 14 d before they were killed. MHC-II immunohistochemistry of the frontal cortex of an APP+PS1 transgenic mouse treated with vehicle (A) and NCX-2216 (B) is shown. CD-11 immunohistochemistry of the frontal cortex of an APP+PS1 transgenic mouse treated with vehicle (C) and NCX-2216 (D) is also shown. Scale bar, 100 μm.
