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Interfering with the function of N-cadherin inhibited the proliferation of cultured supporting cells. Cultures were incubated with latex microbeads that were coated with anti-N-cadherin (A) or nonspecific rat IgG (B). Beads coated with anti-N-cadherin bound to the growing edges of the epithelial explants, resulting in reduced numbers of proliferating cells (C). Scale bar, 20 μm.
