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. 2002 May 1;22(9):3765–3775. doi: 10.1523/JNEUROSCI.22-09-03765.2002

Fig. 8.

Fig. 8.

Cumulative time course profiles across the 60 min interval for an EtOH-maintained (A) and saccharin-maintained (B) response relative to the pooled control condition after infusions of 3-PBC in the VP. The data are redrawn from Figure 4B. All 3-PBC infusions suppressed the initiation of the EtOH response during the first 10 and 20 min intervals (p ≤ 0.05). Except for the 0.5 μg dose condition, all 3-PBC infusions continued to significantly suppress the response throughout the 30–60 min intervals (p ≤ 0.05). In contrast to the EtOH-maintained response, except for the 40 μg dose condition (p < 0.05), none of the 3-PBC infusions altered the response maintained by saccharin at the 10 min interval (p > 0.05) (see Results). Similar to its effect on the EtOH-maintained response, the suppression with the 40 μg dose was sustained throughout the remainder of the 60 min session (p ≤ 0.05) (see Results).BL, Baseline.