Fig. 3.
Effects of a series 3β-hydroxysteroids on 2 μm GABA responses in the presence and absence of 3α5αP. A, Effects of several 3β-hydroxysteroids (10 μm) against potentiation induced by 3α5αP (3 μm) in the presence of 2 μm GABA. For these data, the normalizing response (IN, representing 0 on the y-axis) was the current in the combined presence of 2 μm GABA plus 3 μm3α5αP (n = 6). B, Effects of several 3β-hydroxysteroids on responses to 2 μm GABA alone. Most compounds were effectively inert at 10 μm, except for 3β5βP, which slightly potentiated responses to 2 μm GABA. IN represented the response to 2 μm GABA alone (n = 5).