Skip to main content
. 2002 May 1;22(9):3795–3805. doi: 10.1523/JNEUROSCI.22-09-03795.2002

Fig. 7.

Fig. 7.

Inhibition of fully kindled seizures by DOC and THDOC: reversal of DOC but not THDOC by finasteride. A, Mice that exhibited stage 5 seizures on 3 consecutive days received an intraperitoneal injection of vehicle or DOC (50–100 mg/kg) 30 min before stimulation on days 1 and 3 of stimulation. Some animals received finasteride (10 or 30 mg/kg) 1 hr before DOC.B, Similar experiment to A except that THDOC (3, 10, or 20 mg/kg 15 min before stimulation) was substituted for DOC. Each bar represents the mean ± SEM of data from six to eight animals. *p < 0.05, **p < 0.01 versus vehicle (Veh);#p < 0.05 versus DOC (100 mg/kg) alone group (Mann–Whitney U test).