Skip to main content
. 2002 May 1;22(9):3795–3805. doi: 10.1523/JNEUROSCI.22-09-03795.2002

Fig. 9.

Fig. 9.

Currents evoked by THDOC are blocked by the GABAA receptor antagonists picrotoxin (PTX) and bicuculline (BIC).A, Representative current traces showing block of currents activated by 30 μm THDOC in two separate cells by 100 μm PTX (left) and 100 μm BIC (right). B, Fractional block of currents evoked by 30 μm THDOC (left) and 10 μm GABA (right) by PTX and BIC in experiments similar to those shown in A. Peak current amplitudes in the presence of PTX and BIC are normalized to the peak control current amplitudes in the absence of antagonist. Each bar represents the mean ± SEM of data from three to five cells. Mean amplitudes of THDOC- and GABA-evoked currents are 1030 ± 170 pA (n = 5) and 1920 ± 380 pA (n = 5), respectively. Holding potential, −60 mV.