Fig. 7.

Relationship between [¹¹C]NNC 112 BP in DLPFC (x-axis) and performance (AHR) at the 3-back test (y-axis) in healthy controls (left) and in patients with schizophrenia (right). The AHR ranges from 1 (best performance) to −1 (worse performance), with a score of 0 corresponding to performance at chance level. In controls, DLPFC D₁ receptor availability was not associated with performance at the task. In patients with schizophrenia, increased DLPFC D₁ receptor availability was associated with low performance at the task (r² = 0.45; p = 0.008). Note the difference inx-axis scales between controls and patients with schizophrenia. Similar findings were observed with the 2-back (Table5).