Table 4.

[¹¹C]NNC 112 binding potential: principal component analysis

Region	Subregion	Factor 1 (frontocortical)	Factor 2 (striatal)	Factor 3 (thalamolimbic)
Neocortex	DLPFC	0.83	0.00	−0.40
	MPFC	0.73	0.07	−0.09
	OFC	0.67	−0.05	−0.22
	TC	0.65	0.07	0.11
	PC	0.59	0.00	0.21
	OC	0.49	0.04	0.35
Limbic/paralimbic	ACC	0.43	0.06	0.32
	AMY	0.31	0.04	0.42
	HIP	−0.19	−0.13	0.82
	PHG	0.44	−0.11	0.40
Striatum	DCA	0.07	0.81	−0.18
	DPU	0.00	0.81	0.13
	VST	−0.19	0.89	−0.04
Thalamus		−0.16	0.01	0.89

Values are regional weights for the three factors derived from principal component analysis of the entire sample (n = 32). DLPFC, Dorsolateral prefrontal cortex; MPFC, medial prefrontal cortex; OFC, orbitofrontal cortex; TC, temporal cortex; PC, parietal cortex; OC, occipital cortex; ACC, anterior cingulate cortex; AMY, amygdala; HIP, hippocampus; PHG, parahippocampal gyrus; DCA, dorsal caudate; DPU, dorsal putamen; VST, ventral striatum.