Fig. 5.

Kainic acid induced release of NT-3 from axon terminals in vivo. Injection of kainic acid (KA) in the eye increased the amount of NT-3 that was released from retinotectal terminals compared with PBS-treated controls (+PBS). The KA-induced release of NT-3 was prevented by injection of tetrodotoxin (TTX) in the eye 15 min before KA injection when compared with PBS injections as a control for TTX. The number of independent experiments is indicated on each bar. Error bars indicate SEM. Statistical significance compared with +PBS(••) or the KA+PBS condition (§§) was determined by ANOVA withp ≤ 0.01 (••, §§).