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. 2002 Feb 1;22(3):1146–1154. doi: 10.1523/JNEUROSCI.22-03-01146.2002

Fig. 2.

Fig. 2.

Somatic expression of withdrawal from THC after SR 141716A administration (10 mg/kg, i.p.) is similar in MOR −/−, DOR −/−, and KOR −/− mice and in their respective wild-type controls. Mice received a chronic administration of vehicle or THC (20 mg/kg, i.p., twice daily) for 6 d. Values are expressed as mean ± SEM of global withdrawal scores calculated by giving to each individual sign a proportional weight. Number of mice per group from 10 to 14. ★★★p < 0.001, comparison between treatments (one-way ANOVA).