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KOR −/− mice show place preference to THC (1 mg/kg, i.p.), without priming exposure, whereas their wild-type controls do not. Values are expressed as mean ± SEM. Number of mice per group from 9 to 10. Scores calculated as the difference between test and preconditioning time spent in the drug-paired compartment. ★p < 0.05, comparison between treatments; ⋆p < 0.05, comparison between genotypes (one-way ANOVAs).
