Table 2.
Two-way ANOVA of place conditioning scores to THC of mice lacking μ-, δ-, or κ-opioid receptor
| MOR | DOR | KOR | ||||
|---|---|---|---|---|---|---|
| F | p | F | p | F | p | |
| Genotype (G) | F(1,81) = 0.503 | p = 0.480 | F(1,70) = 0.02 | p = 0.887 | F(1,68) = 2.879 | p = 0.095 |
| Treatment (T) | F(1,81) = 10.04 | p < 0.001 | F(2,70) = 30.66 | p < 0.001 | F(2,68) = 21.261 | p < 0.001 |
| G × T | F(2,81) = 6.516 | p < 0.01 | F(2,70) = 0.351 | p = 0.266 | F(2,68) = 3.391 | p < 0.05 |
Two-way ANOVA with treatment and genotype as between-subjects factors. See Materials and Methods for details. Overall significant effects of treatment are observed in the three strains of mice. A significant interaction between genotype and treatment is observed in MOR and KOR strains.