. Author manuscript; available in PMC: 2019 Sep 24.

Published in final edited form as: J Midwifery Womens Health. 2019 Jan 16;64(1):55–67. doi: 10.1111/jmwh.12935

Table 4.

Influences of Maternal Obesity on Time to Birth and Medication Dosage by Labor Inducing Agent

Study	BMI Ranges kg/m²	Time to Birth h	P Value	Medication Dosage in Labor	P Value
Prostaglandins
Gauthier et al, 2012²³	20–25	21.20 (17.18)^a,b		1.2 (0.3)^c
	≥30	26.25 (19.22)^a,b	.0258	1.4(0.6)^c	.0126
Lassiter et al, 2016²⁴	<30	17.72 (7.3)^a,b		1.59^d
	30–0	20.01 (8.3)^a,b		2.05^d
	≥40	22.90 (11.6)^a,b	.0001	2.32^d	.003
O’Dwyer et al, 2013²⁷	20–29	6.10^a,e		2.5^f
	Overweight	6.00^a,e		2.7^f
	>30	6.60^a,e	NS	2.8^f	NS
Transcervical catheters
Anabusi et al, 2016²⁰	≤30	16.00^g		Not applicable
	>30	16.95^g	.092
Oxytocin
Lassiter et al, 2016²⁴	<30	17.72 (7.3)^a,b		7.17^a,h
	30–40	20.01 (8.3)^a,b		8.54^a,h
	>40	22.90 (11.6)^a,b	.0001	10.39^a,h	.023
Maeder et al, 2017²⁸	<25	13.96 (8.10)^a,b		6.37 (7.06)^a,h
	25–29.9	16.00 (7.54)^a,b		5.98 (5.00)^a,h
	≥30	18.30 (8.65)^a,b	.018	7.50 (6.49)^a,h	.252
O’Dwyer et al, 2013²⁷	20–25	6.10^a,e		Not reported
	Overweight	6.00^a,e
	>30	6.60^a,e	NS
Pevzner et al, 2009²¹	<30	22.70 (11.4–39.6)^b,g		2.6 (0.4–13.5)^g,h
	30–39	24.90 (12.2–43.0)^b,g		3.5 (0.3–15.8)^g,h
	>40	27.00 (12.9–50.4)^b,g	<.001	5.0 (0.4–20.9)^g,h	<.001

Abbreviations: BMI, body mass index; NS, not significant.

Mean (SD, if reported).

Time from labor induction to birth.

Mean (SD) number of prostaglandin doses.

Mean number of doses of misoprostol.

Time in first stage of labor for nulliparous women.

Mean prostaglandin dose for nulliparous women.

Median (10%−90% range, if reported).

Total units of oxytocin.