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Introduction of OA. (A) Current OA treatment, including surgery, drugs, diet, patient education, and exercise. (B) Normal parasagittal section of the knee. (C) Schematic illustration of osteoarthritis. The pathobiology of OA and potential occurring sites in human body. Compared to (B), it demonstrates that OA is a disease that affects the entire joint structure, including the articular cartilage, synovium, subchondral bone, joint capsule, and other components of the joint.
