Fig. 3.
Seizure susceptibility of backcrossed Black Swiss mice is independent of hearing thresholds. A, Auditory brainstem response thresholds were measured from BALB/c, CAST/Ei, Black Swiss, and various BS × CAST/Ei progeny (F2 and N2). F2 and N2 mice were tested twice for seizure susceptibility, at 21 d and 4 months of age. Those that seized at both ages are designated Y/Y, and those that seized at 21 d but not at 4 months are designated Y/N. These results suggest that adult onset hearing loss does not correlate with loss of seizure susceptibility.