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Effect of protein synthesis inhibition on the GDNF-induced expression of KCa channels. A, Inhibition of protein synthesis with anisomysin (25 μm) blocks GDNF stimulation of KCa channels. B, Protein synthesis inhibition does not change the expression of voltage-dependent Ca2+ currents. LMNs were dissociated on E8 and maintained in culture for 24 hr in the presence of GDNF with or without anisomycin.
