Table 1.
PGE2-induced Fos-expression by nonserotonergic cell groups in the rRPa and RMg
| Sites | Number of Fos-positive cells | |
|---|---|---|
| Saline | PGE2 | |
| rRPa | ||
| Serotonergic | 11.0 ± 6.1 | 27.0 ± 8.5 |
| Nonserotonergic | 36.7 ± 3.7 | 185 ± 28* |
| RMg | ||
| Serotonergic | 75.7 ± 11 | 96.0 ± 6.0 |
| Nonserotonergic | 43.0 ± 10 | 142 ± 14* |
The data represent the mean ± SEM of three rats per group. PGE2 or saline was injected into the lateral ventricle. Every sixth 20-μm-thick frontal section throughout the medulla oblongata was immunostained (see Fig. 1c) and examined for Fos immunoreactivity in serotonin-immunoreactive cells (Serotonergic) and serotonin-immunonegative cells (Nonserotonergic).
*
Significant difference from saline-administered group;p < 0.05.