Fig. 3.
Effects of blockade of 5-HT1Areceptors on paradoxical sleep in 5-HT1A+/+ (top) and 5-HT1A−/− (bottom) mice during four successive 2 hr periods after treatment. Data (mean ± SEM of 6 and 4 animals, respectively) are expressed as minutes per 2 hr after injection of saline (white bars) or the 5-HT1A antagonist WAY 100635 at the dose of 0.5 mg/kg intraperitoneally (gray bars). *p < 0.05, significantly different from saline; paired Student's t test.