Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mutant presenilin-1 accelerates memory loss in Tg2576 mice. At 4–5 months, Aβinsol was present in all PS1/APP mice but in only ∼20% of APP mice. PS1/APP mice (n = 21) showed significantly worse performance in probe 1 than APP (n = 11), PS1 (n = 14), or nontransgenic (n = 13) mice (*p < 0.05; **p < 0.01; ***p < 0.001).
