Fig. 1.

MMT exposure induces cell death. PC12 cells were exposed to 200 and 500 μm of MMT for 0.5–5 hr at 37°C. After the exposure, cell-free extracellular supernatants were collected, and LDH activity was measured by spectrophotometer. Values represent mean ± SEM for three to five separate experiments in triplicate. Significance was determined by ANOVA followed by Dunnett's post-test between the vehicle-treated group and each treatment group (*p < 0.05).