Table 2.

Filopodial activity in SNb growth cones^2-a

Genotype2-b	Wild type2-c	V12 (low)	V12C40
Length (μm)2-d
Mean	6.44	6.79	6.92
SEM	0.06	0.08	0.09
Maximum	15.6	14.3	18.5
n	1947	887	1023
p versus wild type		<0.01	<0.01
Extension (μm/min)2-d
Mean	3.59	3.98	3.64
SEM	0.10	0.17	0.15
Maximum	17.9	19.9	22.6
n	905	414	480
p versus wild type		0.13	0.78
Retraction (μm/min)2-d
Mean	−3.54	−3.97	−3.79
SEM	0.10	0.16	0.14
Maximum	−20.0	−21.4	−21.8
n	964	434	489
p versus wild type		0.02	0.14
Longevity (sec)2-e
Mean	363	395	351
SEM	33	42	35
n	50	25	39
p versus wild type		0.56	0.81
Angle (°)2-f
Mean	+4.7	−32.8	+5.0
SEM	1.9	6.1	4.7
Maximum	+29	+10	+20
Minimum	−13	−57	−21
n	25	10	10
p versus wild type		<0.01	0.93
Number (#)2-g
Mean (anterior)	1.67	1.93	1.47
SEM (anterior)	0.10	0.06	0.13
p versus wild type		0.07	0.23
Mean (posterior)	3.97	4.08	4.75
SEM (posterior)	0.09	0.08	0.13
p versus wild type		0.43	<0.01
n	410	205	205

^F2-aHour 12–14 embryos coexpressing gapGFP and one of the mutant Cdc42s were dissected, and filopodial activity of SNb growth cones was monitored (32–39 filopodia in four to eight movies per genotype).

^F2-bSee Table 1 for genotypes.

^F2-cTwo parental controls produced similar results (p > 0.5) and were combined together as wild type.

^F2-dSee Table 1 for measurement methods.

^F2-eBased on monitoring individual filopodia through consecutive frames.

^F2-fSee Figure 6 for measurement methods.

^F2-gThe total number of filopodia (length ≥ 2.5 μm). Anterior and posterior directions are as defined in Figure 6.