Comparison between peripheral 18-oxocortisol (18oxoF) and pathologic parameters. A and B, Peripheral 18-oxocortisol (18oxoF) was significantly correlated with the tumor size. C–E, Similarly, peripheral 18oxoF showed positive correlations with the expression of all the steroidogenic enzymes examined. C17 indicates 17α-hydroxylase; CSA, cross-sectional area; CYP11B1, 11β-hydroxylase; CYP11B2, aldosterone synthase; and MD, maximum diameter.