Figure 5.

When rats undergo S1-shock training and S1 extinction before S2–S1-shock training, BLA infusions of cycloheximide administered immediately after serial-order conditioning do not affect consolidation of fear to S2 but impair consolidation of the reconditioned fear to S1. a, Experimental timeline of fear conditioning and tests for fear to S2 and S1 for rats infused with vehicle (n = 14) or cycloheximide (n = 11) after serial-order conditioning. b, Percentage freezing during counterbalanced tests for fear to S2 and S1 on days 9 and 10. Closed squares represent rats treated with vehicle. Open squares represent rats treated with cycloheximide. Data are mean ± SEM.