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. 2019 Aug 5;132(15):1833–1842. doi: 10.1097/CM9.0000000000000308

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Copyright © 2019 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license.

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Hematoxylin-eosin dyeing of colonic mucosa (original magnification: ×40, ×100, respectively). (A) Blank control group, with normal gland shape and regular structure. (B) Model control group, with obvious crypt destruction and heavy degree of inflammation, damage scope involved submucosa or even deeper. (C) Probiotics group. (D) Synbiotics group. (E) Lactitol group. (F) Probiotics + lactitol group, with different degrees of inflammation, the extent of injury and crypt damage was alleviated than model control group.