Table 1. Baseline characteristics.
| HLAi (n = 50) | ABOi (n = 65) | HLAi+ABOi (n = 5) | Control (n = 428) | LD control (n = 218) | |
|---|---|---|---|---|---|
| Age (y) | 49.0 ± 8.3† | 48.1 ± 12.5 | 46.4 ± 11.5 | 47.7 ± 12.3 | 45.4 ± 12.8 |
| Gender, female (%) | 43 (86.0)*, † | 15 (23.1) | 3 (60.0) | 148 (34.6) | 74 (34.1) |
| Body mass index | 21.2 ± 2.8*, † | 22.4 ± 3.4 | 20.9 ± 1.1 | 22.4 ± 3.5 | 22.6 ± 3.8 |
| Follow up after KT (mo) | 43.7 ± 25.1*, † | 35.3 ± 21.4 | 32.1 ± 25.0 | 35.6 ± 20.4 | 35.1 ± 20.3 |
| Dialysis vintage before KT (mo) | 53.1 ± 79.2† | 8.3 ± 18.3* | 3.9 ± 6.3* | 51.6 ± 86.9 | 9.0 ± 26.2 |
| Primary renal disease, n (%) | |||||
| Glomerulonephritis | 33 (66.0) | 33 (50.8) | 5 (100.0) | 231 (54.0) | 114 (52.3) |
| Diabetes mellitus | 11 (22.0) | 23 (35.4) | 0 (0.0) | 131 (30.6) | 68 (31.2) |
| Hypertension | 2 (4.0) | 5 (7.7) | 0 (0.0) | 30 (7.0) | 15 (6.9) |
| Polycystic kidney disease | 1 (2.0) | 1 (1.5) | 0 (0.0) | 15 (3.5) | 10 (4.6) |
| Others | 3 (6.0) | 3 (4.6) | 0 (0.0) | 21 (4.9) | 11 (5.0) |
| Comorbid conditions, n (%) | |||||
| Hypertension | 13 (26.5) | 8 (12.3) | 0 (0.0) | 83 (19.4) | 42 (19.3) |
| Diabetes mellitus | 37 (74.0) | 37 (56.9) | 4 (80.0) | 286 (66.8) | 145 (66.5) |
| Re-transplant, n (%) | 6 (12.0)*, † | 5 (7.7)† | 1 (20.0) | 14 (3.3) | 4 (1.8) |
| Number of HLA mismatch | 3.4 ± 1.3* | 3.4 ± 1.8* | 3.6 ± 1.1 | 2.9 ± 1.7 | 3.0 ± 1.6 |
| Number of HLA-DR mismatch | 1.2 ± 0.6*, † | 1.2 ± 0.7* | 1.2 ± 0.5 | 1.0 ± 0.7 | 1.0 ± 0.7 |
| Delayed graft function, n (%) | 8 (16.0)† | 0 (0.0)* | 0 (0.0) | 44 (10.3) | 2 (0.9) |
| Donor age (y) | 43.0 ± 14.5† | 46.6 ± 11.7 | 42.2 ± 10.0 | 47.4 ± 14.5 | 48.3 ± 12.1 |
| Donor gender (% male) | 32 (64.0)† | 25 (38.5)* | 3 (60.0) | 231 (54.0) | 95 (43.6) |
| Donor body mass index | 23.3 ± 3.6 | 23.4 ± 3.2† | 25.1 ± 6.1 | 23.6 ± 3.4 | 24.3 ± 3.1 |
| Transplantation type, n (%) | *, † | *, † | * | ||
| Living-related | 20 (40.0) | 29 (44.6) | 2 (40.0) | 141 (32.9) | 141 (64.7) |
| Living-unrelated | 15 (30.0) | 36 (55.4) | 3 (60.0) | 77 (18.0) | 77 (35.3) |
| Deceased | 15 (30.0) | 0 (0.0) | 0 (0.0) | 210 (49.1) | 0 (0.0) |
*P<0.05 vs. control.
†P<0.05 vs. LD control.
Continuous variables are shown as means ± standard deviation.
Abbreviations: HLAi, HLA-incompatible; ABOi, ABO-incompatible; LD, living-donor; KT, kidney transplantation.