Table 2. Inflammatory markers (TNF-α, IL-6, hsCRP) and endothelial dysfunction markers (E-selectin, ICAM-1, VCAM-1) between MetS and non-MetS patients by gender.
| Male (N = 88) | Female (N = 117) | |||||
|---|---|---|---|---|---|---|
| non-MS (N = 51) |
MS (N = 37) |
P-value | non-MS (N = 70) |
MS (N = 47) |
P-value | |
| Inflammatory markers | ||||||
| TNF-α(ng/ml) | 2.92 (1.90, 3.68) | 3.34 (1.70, 4.51) | 0.432 | 2.92 (1.67, 3.58) | 2.64 (1.23, 4.23) | 0.956 |
| IL-6 (pg/ml) | 1.22 (0.73, 2.66) | 2.07 (1.25, 4.17) | 0.023 | 1.07 (0.50, 2.22) | 1.88 (0.88, 2.79) | 0.023 |
| hsCRP (mg/dl) | 0.38 (0.27, 0.75) | 0.49 (0.40, 0.98) | 0.038 | 0.47 (0.27, 1.09) | 1.03 (0.51, 2.19) | < 0.001 |
| Endothelial dysfunction markers | ||||||
| E-selectin (ng/ml) | 45.8 (33.7, 66.0) | 55.9 (37.7, 80.9) | 0.075 | 40.0 (30.0, 51.4) | 56.8 (31.3, 81.0) | < 0.001 |
| VCAM-1 (ng/ml) | 457.0 (307.6, 669.6) | 546.1 (348.8, 795.8) | 0.157 | 366.3 (239.8, 570.2) | 544.3 (287.7, 846.0) | 0.041 |
| ICAM-1 (ng/ml) | 252.3 (208.8, 320.9) | 269.0 (207.4, 326.5) | 0.636 | 252.0 (187.9, 295.2) | 253.3 (205.6, 321.3) | 0.305 |