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. 2019 Sep 24;14(9):e0222228. doi: 10.1371/journal.pone.0222228

Table 3. Single agent dose response IC50s at 24-hours and 96-hours after treatment, ± standard error of the mean.

Tx A673 TC32 Top Concentration Cmax (ng/ml)
Day 2 Day 5 Day 2 Day 5
MTIC 18889 ± 3240 18915 ± 3672 15547 ± 7867 9447 ± 4045 250 276
SN38 40 ± 33 0.77 ± 0 4.0 ± 0.5 2.6 ± 0.2 4 30
SP2509 4222 ± 863 1171 ± 212 2375 ± 221 1238 ± 89 1000 3000
Vincristine 0.73 ± 0.25 0.79 ± 0.03 6.2 ± 1.4 2.0 ± 0.3 1 40