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. 2019 Sep 24;14(9):e0222895. doi: 10.1371/journal.pone.0222895

Table 2. Characteristics of the study population among tertiles of nonmethane hydrocarbons (NMHC) exposure.

Characteristics Tertiles of average daily NMHCa, n (%) P valueb Total
(n = 837,917)
T1 (lowest)
(n = 251,321)
T2
(n = 294,887)
T3 (highest)
(n = 291,709)
Retinal vein occlusion 383 (0.2) 351 (0.1) 773 (0.3) <0.001 1,507 (0.2)
Age, years <0.001
 Mean ± SD 38.3 ± 18.5 27.4 ± 21.9 34.7 ± 18.9 33.2 ± 20.4
Gender <0.001
 Male 130,689 (52.0) 147,136 (49.9) 153,704 (52.7) 431,529 (51.6)
Coronary artery disease 34,868 (13.9) 26,674 (9.0) 28,385 (9.7) <0.001 89,927 (10.9)
Chronic kidney disease 17,570 (7.0) 14,667 (5.0) 16,385 (5.6) <0.001 48,622 (5.9)
Chronic obstructive pulmonary disease 26,852 (10.7) 21,555 (7.3) 21,093 (7.2) <0.001 69,500 (8.4)
Asthma 21,274 (8.5) 31,047 (10.5) 20,635 (7.1) <0.001 72,956 (8.8)
Arrhythmia 36,512 (14.5) 27,802 (9.4) 25,672 (8.8) <0.001 89,986 (10.8)
Cerebrovascular diseases 26,274 (10.5) 19,592 (6.6) 21,817 (7.5) <0.001 67,683 (8.2)
Hypertension 53,729 (21.4) 41,463 (14.1) 44,231 (15.2) <0.001 139,423 (16.7)
Diabetes mellitus 39,624 (15.8) 30,669 (10.4) 34,065 (11.7) <0.001 104,358 (12.6)
Hyperlipidemia 53,559 (21.3) 43,259 (14.7) 46,288 (15.9) <0.001 143,106 (17.0)
Smoking-related diagnosis 16,145 (6.4) 12,068 (4.1) 13,374 (4.6) <0.001 41,587 (5.0)
Morbid obesity 2,147 (0.9) 2,102 (0.7) 2,482 (0.9) <0.001 6,731 (0.8)
Glaucoma 7,127 (2.8) 7,438 (2.5) 7,294 (2.5) <0.001 21,859 (2.6)
Hypercoagulable state 1,921 (0.8) 1,533 (0.5) 1,975 (0.7) <0.001 5,429 (0.7)
Retinal arteriolar disorder 107 (0.04) 88 (0.03) 107 (0.04) 0.046 302 (0.04)

Note: SD, standard deviation.

aTertile values in ppm were as follows: T1 level: < 0.29, T2 level: ≥ 0.29 and < 0.36, T3 level: ≥ 0.36.

bThe chi-squared test or one-way analysis of variance among tertiles of non-methane hydrocarbons.