Skip to main content
. 2019 Sep 12;15(9):e1008067. doi: 10.1371/journal.ppat.1008067

Fig 4. The inferred age of the MTB lineages.

Fig 4

LSD: results of the LSD analysis performed on the individual lineages. BEAST: results of the BEAST analysis performed on the individual lineages (median values). LSD MTBC + aDNA: results of the LSD analysis performed on the complete data set of 6,285 strains + 3 aDNA samples, the age of the MRCA of the individual lineages was identified on the calibrated tree. BEAST MTBC + aDNA: results of the BEAST analysis performed on the random subsample of 500 strains + 3 aDNA samples, the age of the MRCA of the individual lineages was identified on the calibrated tree (median values). The confidence intervals were obtained merging the 95% CI and HPD of all analyses. The shaded area represents the age of the MRCA of the MTB complex obtained with the LSD analyses (with and without aDNA, the two 95% CI were merged). For L5 and L6 we report only the age inferred on the complete MTB complex tree, because when analyzed individually these two data sets showed a lack of temporal structure (they failed the DRT).