Table 3. Antimicrobial resistance patterns of imipenem-resistant and imipenem-susceptible Pseudomonas aeruginosa isolates, Zhejiang Province, China, 2015–2017*.
| Antimicrobial drugs | No. isolates (susceptibility rate, %) |
p value | Total susceptibility rate, % | MIC50, μg/mL |
MIC90, μg/mL |
||||
|---|---|---|---|---|---|---|---|---|---|
| IMP-S | IMP-R | S | R | S | R | ||||
| Piperacillin/tazobactam | 41,145 (85.70) | 23,721 (44.01) | <0.001 | 70.46 | 8 | 64 | 64 | 128 | |
| Ceftazidime | 30,326 (86.26) | 18,348 (47.93) | <0.001 | 71.81 | 4 | 16 | 32 | 64 | |
| Cefepime | 42,492 (89.01) | 24,947 (50.83) | <0.001 | 74.89 | 2 | 8 | 16 | 64 | |
| Aztreonam | 24,215 (68.07) | 13,823 (30.32) | <0.001 | 54.35 | 8 | 32 | 32 | 64 | |
| Amikacin | 42,106 (97.38) | 24,748 (85.69) | <0.001 | 93.06 | 2 | 4 | 8 | 64 | |
| Gentamicin | 41,207 (92.80) | 24,618 (74.29) | <0.001 | 85.88 | 1 | 2 | 4 | 16 | |
| Ciprofloxacin | 42,442 (88.28) | 25,063 (51.64) | <0.001 | 74.67 | 0.25 | 1 | 2 | 4 | |
| Levofloxacin | 41,982 (89.06) | 24,593 (53.17) | <0.001 | 75.80 | 0.5 | 2 | 4 | 8 | |
| Meropenem | 17,166 (96.97) | 9,750 (25.36) | <0.001 | 71.03 | 1 | 8 | 1 | 16 | |
| Colistin | 1,624 (99.08) | 627 (99.04) | NA | 99.07 | 1 | 1 | 1 | 2 | |
| Polymyxin B | 5,012 (98.60) | 3,746 (98.37) | 0.452 | 98.50 | 1 | 1 | 2 | 2 | |
*MIC50 and MIC90 were generated from the minimal inhibitory concentrations of antimicrobial drugs. Bold text indicates p values <0.05. IMP-R, imipenem-resistant; IMP-S, imipenem-susceptible; NA, not applicable; R, resistant; S, susceptible.