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. 2019 Sep 19;87(10):e00442-19. doi: 10.1128/IAI.00442-19

TABLE 4.

Culture results for individual mice treated with ceftriaxone and saline solution commencing 4 weeks after inoculation and then subjected to necropsy 18 months after completion of treatment

Mouse strain Borrelia strain Treatment No. of samples positive/no. testeda
IS Ear UB QM FJ Sp
C3H N40 Ceftriaxone 0/4 0/4 0/4 0/4 0/4 0/4
C3H B31 Ceftriaxone 0/5 0/5 0/5 0/5 0/5 0/5
B6 N40 Ceftriaxone 0/5 0/5 0/5 0/5 1/5b 0/5
B6 B31 Ceftriaxone 0/5 1/5b 0/5 0/5 0/5 0/5
C3H N40 Saline 4/4 4/4 4/4 4/4 4/4 3/4
C3H B31 Saline 3/3 1/3 2/3 2/3 3/3 1/3
B6 N40 Saline 5/5 4/5 1/5 3/5 3/5 2/5
B6 B31 Saline 3/3 3/3 3/3 3/3 3/3 3/3
a

IS, inoculation site; UB, urinary bladder; QM, quadriceps muscle; FJ, front joint; Sp, spleen.

b

Several spirochetes were observed, but we were unable to subculture them.