TABLE 8.
Analysis of plasmid presence in heart base, ventricular muscle, and tibiotarsus of mice infected with B. burgdorferi strain B31 and then treated with ceftriaxone or sham treated with saline solution
| Mouse strain | Treatment/time (h) | Sample typea | Plasmid presenceb
|
||||
|---|---|---|---|---|---|---|---|
| Chrom flaB | lp25 bptA | lp28-1 arp | lp54 ospA | cp32-7 erp23 | |||
| C3H | Saline/12 | VM | + | + | + | + | + |
| B6 | Saline/12 | VM | + | + | + | + | + |
| C3H | Saline/18 | HB | + | + | + | + | + |
| B6 | Saline/18 | HB | + | + | + | + | + |
| C3H | Ceftriaxone/12 | TT | + | − | − | + | − |
| C3H | Ceftriaxone/12 | HB | + | − | − | + | − |
| C3H | Ceftriaxone/12 | TT | + | − | − | + | − |
| B6 | Ceftriaxone/12 | TT | + | − | − | + | + |
| B6 | Ceftriaxone/12 | HB | + | − | − | + | − |
| B6 | Ceftriaxone/12 | TT | + | − | − | + | − |
| C3H | Ceftriaxone/18 | TT | + | − | − | + | − |
| C3H | Ceftriaxone/18 | TT | + | − | − | + | − |
| C3H | Ceftriaxone/18 | TT | + | − | − | + | − |
| B6 | Ceftriaxone/18 | TT | + | − | − | + | − |
| B6 | Ceftriaxone/18 | TT | + | − | − | + | − |
| B6 | Ceftriaxone/18 | TT | + | − | − | + | − |
a
HB, heart base; VM, ventricular muscle; TT, tibiotarsus.
b
Chrom, chromosomal; +, present; −, absent.