FIG 7.

C. albicans growth kinetics. (A and B) Growth kinetic assays of the C. albicans SC5314 (A) and bcr1Δ/Δ (B) strains showed rapid growth when S. mutans supernatant was used. C. albicans in UFTYE–1% sucrose medium showed the lowest growth rate, while Candida in S. mutans-C. albicans supernatants showed a moderate growth rate (relative to that in S. mutans supernatant). (C and D) Growth kinetics of the SC5314 (C) and bcr1Δ/Δ (D) strains were evaluated in UFTYE medium containing 1% sucrose, 1% sucrose plus GtfB, 1% glucose, or 1% fructose. Both strains showed slow growth in UFTYE–1% sucrose medium. Addition of GtfB in UFTYE–1% sucrose significantly increased the growth (versus that with 1% sucrose). Rapid growth of the two strains was observed when they were incubated in UFTYE containing 1% glucose or 1% fructose.