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. Author manuscript; available in PMC: 2020 Oct 15.
Published in final edited form as: Neurosci Lett. 2019 Jul 24;711:134403. doi: 10.1016/j.neulet.2019.134403

Table 1.

Summary of the methylome-wide association studies (MWAS) in AD using Illumina methylation arrays

Article Tissue* Sample type Sample size MWAS Illumina platform
AD Control
Bakulski et al. 2012 FC Bulk-cell 12 12 AD-control Illumina array 27K
Sanchez-Mut et al. 2014 HIP Bulk-cell 15 5 Braak-stage Illumina array 27K
De Jager et al. 2014 DLPFC Bulk-cell 708 Plaque burden Illumina array 450K
Lunnon et al. 2014 EC, STG, PFC, CER, blood Bulk-cell 122 Braak-stage Illumina array 450K
Watson et al. 2016 STG Bulk-cell 34 34 AD-control Illumina array 450K
Smith et al 2018 STG Bulk-cell 142 Braak-stage Illumina array 450K
PFC Bulk-cell 144
Hernandez et al 2018 SFG Neurons 14 18 AD-control Illumina array 450K
Gasparoni et al 2018 OC Neurons or glia 16 15 Braak-stage Illumina array 450K
FC Bulk-cell 37 26
TC Bulk-cell 39 26
Mano et al 2017 ITG Neurons 30 30 AD-control Illumina array 450K
*

FC, frontal cortex; HIP, hippocampus; DLPFC, dorsolateral prefrontal cortex; EC, entorhinal cortex; STG, superior temporal gyrus; PFC, prefrontal cortex; CER, cerebellum; OC, occipital cortex; TC, temporal cortex; ITG, inferior temporal gyrus.