Table 1. Clinical and Treatment Characteristics of Entire Cohort and According to Initial Margin Status.
*Statistically significant value, p <0.05.
| Initial margin status | ||||||
| All patients | Positive | Close (≤3 mm) | Negative | p-value | ||
| n, (%) | 95 (100) | 74 (78) | 14 (15) | 5 (5) | ||
| Median follow-up, months (range) | 33.1 (1.5-256) | 33.1 (1.5-256) | 20.7 (1.6-225) | 70.8 (25-235) | 0.145 | |
| Median age, months (range) | 77 (19-96) | 78 (19-96) | 72 (20-88) | 73 (56-88) | 0.696 | |
| Sex, n (%) | Male | 76 (80) | 18 (24) | 1 (7) | 0 | 0.233 |
| Female | 19 (20) | 56 (76) | 13 (93) | 5 (100) | ||
| Histology, n (%) | Angiosarcoma | 26 (27) | 25 (34) | 1 (7) | 0 | 0.049* |
| Other | 69 (73) | 49 (66) | 13 (93) | 5 (100) | ||
| Excisional biopsy as initial surgery, n (%) | Yes | 57 (60) | 38 (51) | 13 (93) | 4 (80) | 0.004* |
| No | 38 (40) | 36 (49) | 1 (7) | 1 (20) | ||
| Re-excision extent, n (%) | Tissue flap | 16 (17) | 12 (16) | 3 (21) | 1 (20) | 0.036* |
| Skin graft | 28 (30) | 27 (36) | 1 (7) | 0 | ||
| Other | 10 (11) | 9 (12) | 0 | 1 (20) | ||
| None | 41 (43) | 26 (35) | 10 (71) | 3 (60) | ||
| Closest margin location, n (%) | Radial | 2 (2) | 2 (3) | 0 | 0 | 0.361 |
| Deep | 15 (16) | 15 (20) | 0 | 0 | ||
| Both | 4 (4) | 4 (5) | 0 | 0 | ||
| Not reported | 74 (78) | 53 (72) | 14 (100) | 5 (100) | ||
| Re-excision included fascia, n (%) | Yes | 15 (16) | 14 (19) | 1 (7) | 0 | 0.645 |
| No | 5 (5) | 5 (7) | 0 | 0 | ||
| Not reported | 75 (79) | 55 (74) | 13 (93) | 5 (100) | ||
| Radiotherapy, n (%) | Pre-operative | 4 (4) | 4 (5) | 0 | 0 | 0.099 |
| Post-operative | 26 (27) | 25 (34) | 1 (7) | 0 | ||
| None | 65 (68) | 45 (61) | 13 (93) | 5 (100) | ||